Efficacy of sofosbuvir as treatment for yellow fever: protocol for a randomised controlled trial in Brazil (SOFFA study)
Introduction An ongoing outbreak of yellow fever (YF) has been reported in Brazil with 1261 confirmed cases and 409 deaths since July 2017.To date, there is no specific treatment available for YF.Recently published papers describing in vitro crystal beaded candle holder and animal models suggest a potential effect of antiviral drugs (approved for t